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Colleagues,

As reported in MIT Tech Review ... A desktop instrument recently approved by the U.S. Food and Drug Administration might finally bring pharmacogenomic testing--the use of a patient's genetic information for drug prescription decisions--to the mainstream.

This disposable cartridge can detect genetic variations from blood samples. The circles lining the top and bottom are loaded with reagents for different chemical reactions. DNA is isolated from white blood cells and captured on a glass slide within the cartridge.
Credit: Nanosphere


The device, made by Nanosphere, a startup based in Northbrook, Illinois, can, in a matter of hours, detect genetic variations in blood that modulate the effectiveness of some drugs. Dubbed Verigene, the technology employs a combination of microfluidics and nanotechnology, housed in a single plastic cartridge, to pull DNA from a blood sample and then screen it for the relevant sequences....

... "We believe the benefit of our system is that this simple cartridge format could be run in any hospital, even a doctor's office," says William Moffitt, chief executive at Nanosphere. "We're moving complex testing to the point of patient care." Moffitt says Verigene is the first nanotechnology-based microfluidics product capable of analyzing DNA directly from a blood sample...

Read on at: http://www.technologyreview.com/biomedicine/24042/?nlid=2569

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